Description

8-Quinazolinecarboxylic Acid, 1,2,3,4-Tetrahydro-6-Nitro-2,4-Dioxo- is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceutical agents and bioactive molecules, particularly those targeting specific enzymatic pathways. Researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries need this intermediate for constructing complex quinazoline-based scaffolds with potential therapeutic or biological activity.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators with specific modes of action.
• Chemical Biology Probe Development: Serves as a core structure for creating molecular probes to study enzyme function and cellular signaling pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Material Science Research: Potential precursor for the synthesis of organic electronic materials or metal-organic frameworks (MOFs) with specialized properties.

Basic Information

Item	Detail
Product Name	8-Quinazolinecarboxylic Acid, 1,2,3,4-Tetrahydro-6-Nitro-2,4-Dioxo-
CAS No.	331646-89-0
Molecular Formula	C9H5N3O6
Molecular Weight	251.16 g/mol
Synonyms	6-Nitro-1,2,3,4-tetrahydro-2,4-dioxo-8-quinazolinecarboxylic acid; 1,2,3,4-Tetrahydro-6-nitro-2,4-dioxoquinazoline-8-carboxylic acid; 8-Quinazolinecarboxylic acid, 1,2,3,4-tetrahydro-6-nitro-2,4-dioxo-; 6-Nitro-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-8-carboxylic acid; Tetrahydro-6-nitro-2,4-dioxoquinazoline-8-carboxylic acid; CAS 331646-89-0
EINECS	Contact for details

Quality Control

Our 8-Quinazolinecarboxylic Acid, 1,2,3,4-Tetrahydro-6-Nitro-2,4-Dioxo- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.