Description

N1-(6,7-Dimethoxyquinazolin-4-Yl)Benzene-1,4-Diamine is a high-purity pharmaceutical intermediate and research chemical. This compound is of significant commercial interest due to its role as a key building block in the synthesis of complex bioactive molecules, particularly kinase inhibitors. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs. Its precise structure offers a versatile scaffold for developing targeted therapies.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of novel quinazoline-based kinase inhibitors for oncology research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Serves as a reference standard or a starting material for developing enzyme assay probes.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of specialized organic compounds.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Product Name	N1-(6,7-Dimethoxyquinazolin-4-Yl)Benzene-1,4-Diamine
CAS No.	330999-50-3
Molecular Formula	C₁₆H₁₆N₄O₂
Molecular Weight	296.33 g/mol
Synonyms	4-(4-Aminophenylamino)-6,7-dimethoxyquinazoline; 6,7-Dimethoxy-N4-(4-aminophenyl)quinazoline-4-amine; 4-[(4-Aminophenyl)amino]-6,7-dimethoxyquinazoline; 1,4-Benzenediamine, N1-(6,7-dimethoxy-4-quinazolinyl)-; N-(4-Aminophenyl)-6,7-dimethoxy-4-quinazolinamine; 330999-50-3; 6,7-Dimethoxy-4-(4-aminophenylamino)quinazoline
EINECS	Contact for details

Quality Control

Our N1-(6,7-Dimethoxyquinazolin-4-Yl)Benzene-1,4-Diamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.