Description

1,4-Dioxa-8-Azaspiro[4.5]Decan-7-Ylmethanamine is a specialized spirocyclic amine derivative, serving as a crucial building block in advanced organic synthesis. Its unique molecular architecture, featuring both cyclic acetal and amine functionalities, makes it a versatile intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its spirocyclic scaffold which can mimic bioactive conformations.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where its structure can contribute to unique modes of action and improved environmental profiles.
• Ligand and Catalyst Precursor: Serves as a starting material for creating chelating ligands or organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Polymer and Material Science: Incorporated into specialty polymers, resins, or coatings to impart specific chemical resistance, adhesion, or other tailored physical properties.
• Chemical Biology Probe Development: Utilized as a core structure for designing molecular probes and tools to study biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes for high-value compounds.

Basic Information

Product Name	1,4-Dioxa-8-Azaspiro[4.5]Decan-7-Ylmethanamine
CAS No.	330194-76-8
Molecular Formula	C9H16N2O2
Molecular Weight	184.24 g/mol
Synonyms	7-(Aminomethyl)-1,4-dioxa-8-azaspiro[4.5]decane; 1,4-Dioxa-8-azaspiro[4.5]decan-7-ylmethanamine; 8-Azaspiro[4.5]decane-7-methanamine, 1,4-dioxa-; 7-(Aminomethyl)-1,4-dioxa-8-azaspiro[4.5]decane; 330194-76-8; Spirocyclic amino acetal; Aminomethyl-DOASD
EINECS	Contact for details

Quality Control

Our 1,4-Dioxa-8-Azaspiro[4.5]Decan-7-Ylmethanamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.