Description

3-Cyclopentyl-2-(2-propynylsulfanyl)-5,6-dihydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)-4(3H)-one is a complex, high-purity spirocyclic quinazolinone derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated chemical building block and pharmacological research intermediate, valued for its unique structural framework. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery of novel bioactive molecules and heterocyclic compounds.

Application

• Pharmaceutical Research & Development: A key synthetic intermediate in the discovery and optimization of new drug candidates, particularly for targeting specific enzyme families.
• Organic Synthesis Building Block: Used in the construction of complex spirocyclic and fused heterocyclic systems for material science and chemical biology.
• Biochemical Probe Development: Serves as a core scaffold for developing tool compounds and probes to study biological pathways and protein-ligand interactions.
• Agrochemical Intermediate: Potential use in the synthesis of novel active ingredients for crop protection products.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	3-Cyclopentyl-2-(2-propynylsulfanyl)-5,6-dihydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)-4(3H)-one
CAS No.	330179-86-7
Molecular Formula	C25H28N2OS
Molecular Weight	404.57 g/mol
Synonyms	3-Cyclopentyl-2-(prop-2-yn-1-ylthio)-5,6-dihydrospiro[benzo[h]quinazoline-5,1'-cyclopentane]-4(3H)-one; Spiro[benzo[h]quinazoline-cyclopentane] derivative; 2-(Prop-2-ynylsulfanyl)-3-cyclopentyl-5,6-dihydrospiro[benzo[h]quinazoline-5,1'-cyclopentane]-4-one; CAS 330179-86-7; Quinazolinone spirocyclic derivative; 4(3H)-Quinazolinone, 3-cyclopentyl-2-(2-propynylthio)-5,6-dihydrospiro[benzo[h]quinazoline-5,1'-cyclopentane]-
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.