Description

3-(4-Chlorobenzyl)-7-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic compound class. This compound is of significant commercial importance as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential therapeutic agents targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Kinase Inhibitor Development: The benzothienopyrimidine core is a privileged structure in the design of protein kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Active Ingredient Synthesis: Employed in the research and development of new crop protection agents and pesticides.
• Fine Chemical Synthesis: Acts as a specialized building block for creating complex molecules used in material science and specialty chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	3-(4-Chlorobenzyl)-7-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One
CAS No.	329227-50-1
Molecular Formula	C19H17ClN2OS
Molecular Weight	356.87 g/mol
Synonyms	3-[(4-Chlorophenyl)methyl]-7-methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one; 7-Methyl-3-(4-chlorobenzyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one; 3-(4-Chlorobenzyl)-7-methyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one; Benzothieno[2,3-d]pyrimidin-4(3H)-one, 3-[(4-chlorophenyl)methyl]-5,6,7,8-tetrahydro-7-methyl-; CAS 329227-50-1
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorobenzyl)-7-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.