Description

2-(5-Chloro-Thiophen-2-Yl)-Quinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for therapeutic agents targeting specific biological pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, agrochemicals, and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates for therapeutic applications.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic framework for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a potential electron-transport or emissive layer material due to its conjugated quinoline-thiophene structure.
• Material Science: Investigated as a building block for organic semiconductors and conductive polymers.
• Chemical Synthesis: Employed as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Academic & Industrial R&D: Used in research laboratories for exploring new chemical reactions and catalytic processes.

Basic Information

Product Name	2-(5-Chloro-Thiophen-2-Yl)-Quinoline-4-Carboxylic Acid
CAS No.	329222-93-7
Molecular Formula	C14H8ClNO2S
Molecular Weight	289.74 g/mol
Synonyms	2-(5-Chlorothiophen-2-yl)quinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 2-(5-chloro-2-thienyl)-; 2-(5-Chloro-2-thienyl)-4-quinolinecarboxylic acid; Quinoline-4-carboxylic acid, 2-(5-chlorothiophen-2-yl)-; 329222-93-7; 2-(5-Chloro-thiophen-2-yl)-quinoline-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(5-Chloro-Thiophen-2-Yl)-Quinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.