Description

2-Ethyl-3-(4-Fluorophenyl)Quinazolin-4(3H)-One is a high-purity, fluorinated quinazolinone derivative, a key scaffold in modern pharmaceutical and agrochemical research. Its core value lies in its role as a versatile synthetic intermediate for developing novel active compounds, particularly in kinase inhibitor and antimicrobial research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, especially kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinazolinone core.
• Chemical Biology & Proteomics: Serves as a molecular probe or a precursor for activity-based protein profiling (ABPP) to study enzyme function.
• Material Science Research: Investigated as a precursor for organic electronic materials due to its conjugated aromatic system and potential for functionalization.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting medicinal chemistry and synthetic methodology studies.
• Custom Synthesis & Scale-Up: Supplied for custom manufacturing projects requiring this specific fluorinated heterocycle for pilot or commercial-scale production.

Basic Information

Product Name	2-Ethyl-3-(4-Fluorophenyl)Quinazolin-4(3H)-One
CAS No.	329190-48-9
Molecular Formula	C₁₆H₁₃FN₂O
Molecular Weight	268.29 g/mol
Synonyms	2-Ethyl-3-(4-fluorophenyl)-4(3H)-quinazolinone; 3-(4-Fluorophenyl)-2-ethyl-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 2-ethyl-3-(4-fluorophenyl)-; 2-Ethyl-3-(p-fluorophenyl)quinazolin-4-one; 329190-48-9; 2-Ethyl-3-(4-fluorophenyl)-3,4-dihydroquinazolin-4-one; 2-Ethyl-3-(4'-fluorophenyl)-4-quinazolinone
EINECS	Contact for details

Quality Control

Our 2-Ethyl-3-(4-Fluorophenyl)Quinazolin-4(3H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.