Description

2-Hydroxy-N'-[(E)-(3-Methylthiophen-2-Yl)Methylidene]-2-Phenylacetohydrazide is a specialized organic compound belonging to the class of hydrazide derivatives, characterized by its unique molecular structure incorporating a thiophene ring. This compound matters as a high-value chemical intermediate and research chemical for the development of novel molecules with targeted biological or material properties. It is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and academic research institutions focused on medicinal chemistry and heterocyclic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Ligand Synthesis: Acts as a precursor for creating complex ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in research to develop molecular probes for studying enzyme inhibition or protein interactions.
• Academic & Institutional R&D: A valuable compound for fundamental research in organic synthesis and heterocyclic chemistry at universities and government labs.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or specialty polymers due to its conjugated system.

Basic Information

Product Name	2-Hydroxy-N'-[(E)-(3-Methylthiophen-2-Yl)Methylidene]-2-Phenylacetohydrazide
CAS No.	328910-25-4
Molecular Formula	C₁₅H₁₆N₂O₂S
Molecular Weight	288.36 g/mol
Synonyms	2-Hydroxy-2-phenyl-N'-[(1E)-1-(3-methyl-2-thienyl)ethylidene]acetohydrazide; Mandelic acid (3-methyl-2-thienyl)methylene hydrazide; (E)-2-Hydroxy-N'-(3-methylthiophen-2-yl)methylene)-2-phenylacetohydrazide; 2-Phenyl-2-hydroxy-N'-[(E)-1-(3-methyl-2-thienyl)ethylidene]acetohydrazide; Hydrazide derivative of mandelic acid and 3-methylthiophene-2-carboxaldehyde; CAS 328910-25-4
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-N'-[(E)-(3-Methylthiophen-2-Yl)Methylidene]-2-Phenylacetohydrazide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency suitable for research and development applications. Standard quality checks include HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.