Description

trans-3'-Oxo-Spiro[Cyclohexane-1,1'(3'H)-Isobenzofuran]-4-Carboxylic Acid is a high-purity, synthetically valuable spirocyclic compound characterized by its unique fused ring system. This chemical serves as a critical advanced pharmaceutical intermediate and a versatile building block for complex organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing novel molecular architectures with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used as a sophisticated scaffold for developing new generation herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies due to its complex, three-dimensional spiro structure.
• Material Science Precursor: Potential starting material for synthesizing specialized polymers or ligands with unique steric and electronic properties.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis manufacturers for client-specific projects and process development.

Basic Information

Product Name	trans-3'-Oxo-Spiro[Cyclohexane-1,1'(3'H)-Isobenzofuran]-4-Carboxylic Acid
CAS No.	328233-08-5
Molecular Formula	C14H14O4
Molecular Weight	246.26 g/mol
Synonyms	4-Carboxy-3'-oxospiro[cyclohexane-1,1'-isobenzofuran]; trans-3'-Oxospiro[cyclohexane-1,1'(3'H)-isobenzofuran]-4-carboxylic acid; 3'-Oxospiro[cyclohexane-1,1'(3'H)-isobenzofuran]-4-carboxylic acid, trans-; Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]-4-carboxylic acid, 3'-oxo-, trans-; 328233-08-5; (trans)-3'-Oxo-spiro[cyclohexane-1,1'(3'H)-isobenzofuran]-4-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of trans-3'-Oxo-Spiro[Cyclohexane-1,1'(3'H)-Isobenzofuran]-4-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.