Description

3-(4-Fluorophenyl)-2-{3-Nitrophenyl}-2,3-Dihydro-4(1H)-Quinazolinone is a high-purity, specialized heterocyclic organic compound with the CAS number 328090-76-2. This chemical serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in medicinal chemistry research. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing novel active ingredients in crop protection and pest management products.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-batch clinical trial materials.

Basic Information

Product Name	3-(4-Fluorophenyl)-2-{3-Nitrophenyl}-2,3-Dihydro-4(1H)-Quinazolinone
CAS No.	328090-76-2
Molecular Formula	C20H14FN3O3
Molecular Weight	363.34 g/mol
Synonyms	2,3-Dihydro-3-(4-fluorophenyl)-2-(3-nitrophenyl)-4(1H)-quinazolinone; 3-(4-Fluorophenyl)-2-(3-nitrophenyl)-1,2,3,4-tetrahydroquinazolin-4-one; 328090-76-2; Quinazolinone derivative, 3-(4-fluorophenyl)-2-(3-nitrophenyl)-2,3-dihydro-4(1H)-one; 4(1H)-Quinazolinone, 2,3-dihydro-3-(4-fluorophenyl)-2-(3-nitrophenyl)-
EINECS	Contact for details

Quality Control

Our production of 3-(4-Fluorophenyl)-2-{3-Nitrophenyl}-2,3-Dihydro-4(1H)-Quinazolinone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.