Description

(E)-tert-Butyl 2-(Pyridin-2-Ylmethylene)Hydrazinecarboxylate is a high-purity, protected hydrazine derivative that serves as a critical synthetic intermediate. Its value lies in providing a stable, reactive handle for constructing complex nitrogen-containing heterocycles and active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to streamline complex synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of pyrazole, pyrazoline, and other fused nitrogen heterocycles found in drug candidates.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides that require specific hydrazone-based scaffolds.
• Ligand Precursor: Serves as a starting material for the preparation of bidentate and tridentate ligands used in catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of functional organic molecules and polymers with tailored electronic or photophysical properties.
• Chemical Biology Probes: Useful for constructing molecular probes and bioconjugation reagents due to its reactive hydrazone functionality.

Basic Information

Product Name	(E)-tert-Butyl 2-(Pyridin-2-Ylmethylene)Hydrazinecarboxylate
CAS No.	328011-57-0
Molecular Formula	C11H15N3O2
Molecular Weight	221.26 g/mol
Synonyms	tert-Butyl (E)-2-[(pyridin-2-yl)methylidene]hydrazinecarboxylate; (E)-tert-Butyl 2-(Pyridin-2-Ylmethylene)Hydrazinecarboxylate; tert-Butyl (E)-2-(2-Pyridylmethylene)hydrazinecarboxylate; 2-Pyridinecarboxaldehyde, 2-[(1,1-dimethylethoxy)carbonyl]hydrazone; Boc-Hydrazone of 2-Pyridinecarboxaldehyde; (E)-N'-tert-Butoxycarbonyl-2-pyridinecarboximidohydrazide
EINECS	Contact for details

Quality Control

Our (E)-tert-Butyl 2-(Pyridin-2-Ylmethylene)Hydrazinecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.