Description

(1S, 2S, 5R, 7S)-2,8,8,Trimethyl-3-Azatricyclo[5.1.1.0(2,5)]Nonane-4-One is a high-purity, stereochemically defined organic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its rigid, complex tricyclic structure makes it a valuable building block for the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. This product is essential for research and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific stereochemistry and molecular complexity into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used as a precursor for developing novel, stereoselective pesticides and herbicides with enhanced efficacy.
• Catalyst & Ligand Development: Serves as a sophisticated backbone for creating novel chiral catalysts and ligands used in asymmetric synthesis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring precise stereochemical control.
• Academic & R&D: A valuable compound for methodological research in organic synthesis and stereochemistry at universities and corporate R&D centers.

Basic Information

Product Name	(1S, 2S, 5R, 7S)-2,8,8,Trimethyl-3-Azatricyclo[5.1.1.0(2,5)]Nonane-4-One
CAS No.	328010-05-5
Molecular Formula	C12H19NO
Molecular Weight	193.29 g/mol
Synonyms	2,8,8-Trimethyl-3-azatricyclo[5.1.1.02,5]nonan-4-one; (1S,2S,5R,7S)-2,8,8-Trimethyl-3-azatricyclo[5.1.1.02,5]nonan-4-one; Tricyclic Lactam Derivative; Chiral Tricyclic Lactam; 3-Azatricyclo[5.1.1.02,5]nonane-4-one, 2,8,8-trimethyl-, (1S,2S,5R,7S)-
EINECS	Contact for details

Quality Control

Our production of (1S, 2S, 5R, 7S)-2,8,8,Trimethyl-3-Azatricyclo[5.1.1.0(2,5)]Nonane-4-One adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.