Description

[2-(4-Fluorophenyl)Quinolin-4-Yl](4-Methylpiperazin-1-Yl)Methanone is a high-purity, advanced pharmaceutical intermediate with the CAS number 327976-35-2. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted therapeutic agents. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the development of kinase-targeted small molecule inhibitors.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological pathways and protein functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Academic Research: Used in university and institutional labs for exploratory organic synthesis and novel heterocyclic chemistry.

Basic Information

Product Name	[2-(4-Fluorophenyl)Quinolin-4-Yl](4-Methylpiperazin-1-Yl)Methanone
CAS No.	327976-35-2
Molecular Formula	C21H20FN3O
Molecular Weight	349.41 g/mol
Synonyms	4-(4-Fluorophenyl)-2-(4-methyl-1-piperazinyl)carbonylquinoline; 2-(4-Fluorophenyl)-4-[(4-methyl-1-piperazinyl)carbonyl]quinoline; (2-(4-Fluorophenyl)quinolin-4-yl)(4-methylpiperazin-1-yl)methanone; Methanone, [2-(4-fluorophenyl)-4-quinolinyl](4-methyl-1-piperazinyl)-; CAS 327976-35-2; 327976-35-2
EINECS	Contact for details

Quality Control

Our [2-(4-Fluorophenyl)Quinolin-4-Yl](4-Methylpiperazin-1-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.