Description

2-(Benzylsulfanyl)-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclopentan]-4(6H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic quinazoline core. This compound is of significant value for its role in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and biotechnology sectors for creating new chemical entities and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and the development of novel chemical libraries for high-throughput screening.
• Organic Synthesis: Serves as a sophisticated precursor for constructing complex heterocyclic frameworks in academic and industrial laboratories.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study enzyme inhibition or receptor binding.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules.

Basic Information

Product Name	2-(Benzylsulfanyl)-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclopentan]-4(6H)-One
CAS No.	327167-65-7
Molecular Formula	C24H22N2OS
Molecular Weight	386.51 g/mol
Synonyms	2-(Benzylthio)-3H-spiro[benzo[h]quinazoline-5,1'-cyclopentan]-4(6H)-one; 2-(Phenylmethylthio)-3H-spiro[benzo[h]quinazoline-5,1'-cyclopentan]-4(6H)-one; 327167-65-7; Benzo[h]quinazoline spirocyclopentane derivative; Spiro[benzo[h]quinazoline-5,1'-cyclopentan]-4(6H)-one, 2-(benzylthio)-3H-
EINECS	Contact for details

Quality Control

Our 2-(Benzylsulfanyl)-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclopentan]-4(6H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.