Description

2,2,2-Trifluoro-1-Naphthalen-1-Yl-Ethylamine is a specialized fluorinated amine building block that combines a naphthalene core with a trifluoroethylamine moiety. This unique structure makes it a valuable intermediate for synthesizing advanced molecules with tailored electronic and steric properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the fluorine-enhanced properties.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the naphthalene and fluorine groups contribute to biological activity and environmental stability.
• Ligand Synthesis: Serves as a precursor for creating chiral ligands and catalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science: Incorporated into the design of specialty polymers, liquid crystals, and organic electronic materials to modify solubility and charge transport characteristics.
• Fluorine Chemistry Research: An essential reagent for studying structure-activity relationships (SAR) and introducing trifluoroethyl groups into complex molecular architectures.

Basic Information

Product Name	2,2,2-Trifluoro-1-Naphthalen-1-Yl-Ethylamine
CAS No.	326594-18-7
Molecular Formula	C₁₂H₁₀F₃N
Molecular Weight	225.21 g/mol
Synonyms	1-(1-Naphthyl)-2,2,2-trifluoroethylamine; 1-(2,2,2-Trifluoroethyl)naphthalene; α-(Trifluoromethyl)-1-naphthalenemethylamine; 2,2,2-Trifluoro-1-(naphthalen-1-yl)ethan-1-amine; Naphthalen-1-yl(2,2,2-trifluoroethyl)amine; 1-(1-Naphthyl)-2,2,2-trifluoroethanamine; 326594-18-7
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to cGMP principles for production and quality management where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.