Description

n-Trityl-1,4-diaminobutane diacetate is a protected diamine derivative, serving as a crucial building block in advanced organic synthesis. This compound is valued for its role in facilitating the controlled introduction of the 1,4-diaminobutane (putrescine) moiety into complex molecular architectures, particularly in pharmaceutical and fine chemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active pharmaceutical ingredients (APIs), bioactive molecules, and specialized polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of polyamine analogs, enzyme inhibitors, and receptor ligands in drug discovery programs.
• Peptidomimetic Synthesis: Used to incorporate a protected diamine spacer into peptide backbones, modifying stability and biological activity.
• Linker Chemistry: Serves as a versatile building block in solid-phase synthesis and for constructing dendrimers or molecular scaffolds.
• Protecting Group Strategy: The trityl (triphenylmethyl) group provides orthogonal protection for primary amines, enabling selective reactions in multi-step syntheses.
• Bioconjugation: Potential use in creating chemical linkers for antibody-drug conjugates (ADCs) or diagnostic probes.
• Academic & Industrial Research: Fundamental research tool in medicinal chemistry and chemical biology for exploring polyamine metabolism and function.

Basic Information

Product Name	n-Trityl-1,4-Diaminobutane Diacetate
CAS No.	325708-23-4
Molecular Formula	C31H34N2O4
Molecular Weight	498.61 g/mol
Synonyms	N1,N4-Ditritylputrescine diacetate; 1,4-Diaminobutane, N1,N4-bis(triphenylmethyl)-, diacetate; N,N'-Bis(trityl)-1,4-butanediamine diacetate; N1,N4-Bis(trityl)butane-1,4-diamine diacetate; Trityl-protected putrescine diacetate; N-Trityl-1,4-diaminobutane acetate; 325708-23-4
EINECS	Contact for details

Quality Control

Our n-Trityl-1,4-diaminobutane diacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.