Description

N1-Tritylpropane-1,3-Diamine Acetate is a high-purity, protected diamine derivative primarily used as a critical building block in advanced organic synthesis. Its value lies in the trityl (triphenylmethyl) protecting group, which offers excellent stability and selective deprotection capabilities for primary amine functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly in the development of active pharmaceutical ingredients (APIs), complex peptides, and specialized polymers where controlled amine reactivity is required.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a protected diamine linker or spacer in solid-phase and solution-phase peptide synthesis.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating chelating ligands, organocatalysts, and metal complexes.
• Polymer Modification: Employed to introduce amine functionality into polymer backbones for creating specialty polyamides, epoxy hardeners, or functionalized surfaces.
• Bioconjugation: Useful in the development of antibody-drug conjugates (ADCs) and other bioconjugate platforms where a stable, protected amine handle is needed.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing molecular libraries.

Basic Information

Product Name	N1-Tritylpropane-1,3-Diamine Acetate
CAS No.	325143-22-4
Molecular Formula	C26H30N2O2 • (C2H4O2)x or C28H34N2O4 (for acetate salt)
Molecular Weight	462.58 g/mol (for C28H34N2O4)
Synonyms	N1-Trityl-1,3-diaminopropane Acetate; N-(Triphenylmethyl)-1,3-propanediamine Acetate; 3-[(Triphenylmethyl)amino]propylamine Acetate; Trt-Dap-NH2 Acetate; Nα-Trityl-1,3-diaminopropane Acetate; N-Tritylpropane-1,3-diamine Acetate Salt; 1,3-Propanediamine, N1-(triphenylmethyl)-, acetate (1:?); CAS 325143-22-4
EINECS	Contact for details

Quality Control

Our N1-Tritylpropane-1,3-Diamine Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.