Description

N'-[(E)-(4-Fluorophenyl)Methylidene]-1-[(4-Methylphenyl)Sulfonyl]-4-Piperidinecarbohydrazide is a high-purity, specialized organic intermediate of significant interest in advanced chemical synthesis. Its complex sulfonyl and hydrazide-based structure makes it a valuable building block for research and development in pharmaceutical chemistry. This compound is primarily sought by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing complex heterocyclic frameworks.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study enzyme inhibition or receptor-ligand interactions.
• Process Chemistry & Scale-Up: Acts as a defined intermediate for optimizing synthetic routes and scaling up production of target molecules under Good Manufacturing Practice (GMP) conditions.
• Academic & Institutional Research: Utilized in universities and research institutes for investigating new organic reactions and catalytic methodologies involving sulfonamide and hydrazone functionalities.

Basic Information

Product Name	N'-[(E)-(4-Fluorophenyl)Methylidene]-1-[(4-Methylphenyl)Sulfonyl]-4-Piperidinecarbohydrazide
CAS No.	324531-41-1
Molecular Formula	C20H22FN3O3S
Molecular Weight	403.47 g/mol
Synonyms	1-[(4-Methylphenyl)sulfonyl]-4-[(E)-[(4-fluorophenyl)methylene]hydrazinecarbonyl]piperidine; 4-[[(4-Fluorobenzylidene)amino]carbonyl]-1-(p-tolylsulfonyl)piperidine; 1-Tosyl-4-[(E)-N'-(4-fluorobenzylidene)hydrazinecarbonyl]piperidine; 324531-41-1; N'-(4-Fluorobenzylidene)-1-tosylpiperidine-4-carbohydrazide; (E)-N'-(4-Fluorobenzylidene)-1-tosylpiperidine-4-carbohydrazide; 1-(p-Toluenesulfonyl)-4-[(E)-[(4-fluorophenyl)methylene]hydrazinecarbonyl]piperidine
EINECS	Contact for details

Quality Control

Every batch of N'-[(E)-(4-Fluorophenyl)Methylidene]-1-[(4-Methylphenyl)Sulfonyl]-4-Piperidinecarbohydrazide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA), confirming identity, purity, and impurity profile via techniques such as HPLC, NMR, and mass spectrometry, is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.