Description

(S)-α-tert-Butyl-1-Naphthylmethylamine is a chiral amine building block of significant importance in asymmetric synthesis. Its value lies in its rigid, bulky structure, which is highly effective for inducing stereoselectivity in catalytic reactions and creating chiral environments. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• As a chiral ligand or catalyst precursor in asymmetric hydrogenation, alkylation, and other transition metal-catalyzed reactions.
• Utilized as a key chiral building block (C11 synthon) in the multi-step synthesis of complex pharmaceutical compounds.
• Employed in the research and development of novel agrochemicals and specialty fine chemicals requiring high enantiomeric purity.
• Serves as a chiral resolving agent or auxiliary for the separation of racemic mixtures.
• Used in academic and industrial R&D for methodological studies in organic and medicinal chemistry.
• Potential application in the synthesis of functional materials, such as chiral polymers or liquid crystals.

Basic Information

Product Name	(S)-α-tert-Butyl-1-Naphthylmethylamine
CAS No.	324034-56-2
Molecular Formula	C₁₆H₂₁N
Molecular Weight	227.35 g/mol
Synonyms	(S)-1-[(1-Naphthyl)methyl]-2-methylpropan-2-amine; (S)-1-(1-Naphthylmethyl)-2-methyl-2-propylamine; (S)-α-(tert-Butyl)-1-naphthalenemethanamine; (S)-(-)-α-tert-Butyl-1-naphthalenemethylamine; (S)-Tert-Butyl(1-naphthylmethyl)amine; (S)-TBNMA; (S)-1-Naphthylmethyl-tert-butylamine; (S)-1-(tert-Butylaminomethyl)naphthalene
EINECS	Contact for details

Quality Control

Our (S)-α-tert-Butyl-1-Naphthylmethylamine is produced under strict quality management protocols to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Each batch is characterized by advanced analytical techniques including chiral HPLC, NMR, and GC/MS. Certificates of Analysis (COA) detailing purity, enantiomeric excess (ee), and impurity profiles are provided to guarantee batch-to-batch consistency and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.