Description

4-Amine-7-Chloromethylquinazoline is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its dual reactive sites, the amine and chloromethyl groups, which enable precise molecular construction in complex chemical pathways. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tyrosine kinase inhibitors and other targeted cancer therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the quinazoline core for bioactivity.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for creating functionalized polymers and advanced organic materials with specific electronic properties.
• Dye & Pigment Industry: Intermediate for synthesizing specialized quinazoline-based colorants and fluorescent markers.

Basic Information

Product Name	4-Amine-7-Chloromethylquinazoline
CAS No.	323591-38-4
Molecular Formula	C9H8ClN3
Molecular Weight	193.63 g/mol
Synonyms	7-(Chloromethyl)quinazolin-4-amine; 4-Amino-7-(chloromethyl)quinazoline; 4-Quinazolinamine, 7-(chloromethyl)-; 7-Chloromethyl-4-quinazolinamine; 4-Amino-7-chloromethylquinazoline; 7-Chloromethylquinazolin-4-ylamine; Quinazoline, 4-amino-7-(chloromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Amine-7-Chloromethylquinazoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.