Description

(2E)-3-[4-Methoxy-3-(Piperidin-1-Ylsulfonyl)Phenyl]Acrylic Acid CAS NO 321979-11-7 is a high-purity, non-racemic synthetic intermediate featuring a piperidine sulfonamide and a cinnamic acid backbone. This compound matters for its role as a critical building block in the development of targeted small-molecule pharmaceuticals, particularly in kinase inhibitor research. Pharmaceutical R&D and fine chemical synthesis laboratories need this material for lead optimization and process chemistry due to its unique structural motifs that can impart specific binding and pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in lead compound optimization and structure-activity relationship (SAR) studies.
• Process Development: Serves as a starting material or advanced intermediate in scaling up API (Active Pharmaceutical Ingredient) synthesis.
• Biochemical Tool Compound: Potential use in developing probes for studying enzyme function and cellular signaling pathways.
• Fine Chemical Synthesis: Employed in constructing complex molecules for agrochemical or advanced material research.

Basic Information

Product Name	(2E)-3-[4-Methoxy-3-(Piperidin-1-Ylsulfonyl)Phenyl]Acrylic Acid
CAS No.	321979-11-7
Molecular Formula	C15H19NO5S
Molecular Weight	325.38 g/mol
Synonyms	(E)-3-(4-Methoxy-3-(piperidine-1-sulfonyl)phenyl)acrylic acid; 3-(4-Methoxy-3-(piperidin-1-ylsulfonyl)phenyl)-2-propenoic acid; trans-3-[4-Methoxy-3-(1-piperidinylsulfonyl)phenyl]-2-propenoic Acid; (2E)-3-[4-Methoxy-3-(Piperidin-1-Ylsulfonyl)Phenyl]Acrylic Acid; 321979-11-7; 4-Methoxy-3-(piperidin-1-ylsulfonyl)cinnamic acid
EINECS	Contact for details

Quality Control

Our (2E)-3-[4-Methoxy-3-(Piperidin-1-Ylsulfonyl)Phenyl]Acrylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.