Description

1-Bromo-3-(Vinylsulfonyl)Benzene is a high-value, multi-functional aromatic building block featuring both a reactive bromine substituent and a vinyl sulfone group. This unique bifunctional structure makes it a critical intermediate for the synthesis of advanced materials and active pharmaceutical ingredients (APIs) via cross-coupling and Michael addition reactions. It is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty polymer industries seeking to introduce sulfone and aryl bromide functionalities into complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting kinase inhibition.
• Agrochemical Synthesis: Used in creating advanced herbicides and fungicides with enhanced activity and selectivity.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty polymers, coatings, and functional materials.
• Organic Synthesis Reagent: Employed in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Bioconjugation & Probe Development: Utilized in designing chemical probes and bioconjugates due to the reactivity of the vinyl sulfone group with thiols.
• Liquid Crystal & OLED Materials: A precursor in the development of electronic and photonic materials requiring specific aromatic architectures.

Basic Information

Product Name	1-Bromo-3-(Vinylsulfonyl)Benzene
CAS No.	321976-44-7
Molecular Formula	C8H7BrO2S
Molecular Weight	247.11 g/mol
Synonyms	3-Bromophenyl vinyl sulfone; m-Bromophenyl vinyl sulfone; Vinyl 3-bromophenyl sulfone; 1-Bromo-3-vinylsulfonylbenzene; 3-Bromobenzenesulfonyl ethylene; (3-Bromophenyl)ethenesulfone; Benzene, 1-bromo-3-(vinylsulfonyl)-
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(Vinylsulfonyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.