Description

1-(4-Methoxycarbonylamino-Benzenesulfonyl)-Piperidine-3-Carboxylic Acid is a high-purity, non-natural amino acid derivative featuring a unique sulfonyl-piperidine-carboxylic acid scaffold. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, enabling the development of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of protease inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially protease inhibitors and enzyme modulators.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new pharmacophores.
• Peptidomimetic Development: Serves as a constrained, non-proteinogenic amino acid analog in the design of peptide-like compounds with enhanced metabolic stability.
• Chemical Biology Probes: Utilized in the development of activity-based probes and labeled compounds for target identification and validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals for clients.

Basic Information

Product Name	1-(4-Methoxycarbonylamino-Benzenesulfonyl)-Piperidine-3-Carboxylic Acid
CAS No.	321970-64-3
Molecular Formula	C15H20N2O6S
Molecular Weight	356.40 g/mol
Synonyms	3-Piperidinecarboxylic acid, 1-[[(4-methoxycarbonylamino)phenyl]sulfonyl]-; 1-[(4-Methoxycarbonylaminophenyl)sulfonyl]piperidine-3-carboxylic Acid; 1-(4-(Methoxycarbonylamino)benzenesulfonyl)piperidine-3-carboxylic Acid; Piperidine-3-carboxylic acid, 1-[(4-methoxycarbonylaminophenyl)sulfonyl]-; CAS 321970-64-3
EINECS	Contact for details

Quality Control

Our production of 1-(4-Methoxycarbonylamino-Benzenesulfonyl)-Piperidine-3-Carboxylic Acid adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing comprehensive analytical results, including assay and impurity profiles by HPLC, are provided with every shipment. We support cGMP compliance for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.