Description

n-Acetyllactosamine 6,6’-Disulfate Disodium Salt is a chemically defined, sulfated disaccharide derivative of lactose, a key building block in glycobiology research. This compound is critical for studying and modulating sulfated glycan-protein interactions, which are fundamental to numerous biological signaling and recognition processes. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and diagnostic sectors for applications in drug discovery, enzyme substrate studies, and the synthesis of complex glycoconjugates.

Application

• Glycobiology Research: Essential substrate or inhibitor for studying sulfotransferase and sulfatase enzymes involved in glycan biosynthesis and degradation.
• Drug Discovery: Used in high-throughput screening assays to identify novel therapeutics targeting sulfated carbohydrate-mediated pathways, such as inflammation and viral entry.
• Biomarker Development: Serves as a standard or probe in the development of diagnostic tools for diseases associated with aberrant sulfated glycan expression.
• Enzymatic Synthesis: Acts as a key intermediate or acceptor molecule in the chemoenzymatic synthesis of more complex, biologically relevant sulfated oligosaccharides.
• Structural Studies: Utilized in nuclear magnetic resonance (NMR) and X-ray crystallography to elucidate the three-dimensional structure of carbohydrate-binding proteins.
• Cell Signaling Studies: Applied in vitro to investigate the role of specific sulfated glycans in cell adhesion, growth factor signaling, and immune response modulation.

Basic Information

Product Name	n-Acetyllactosamine 6,6’-Disulfate Disodium Salt
CAS No.	321897-68-1
Molecular Formula	C14H22NNa2O17S2
Molecular Weight	587.48 g/mol
Synonyms	Lactosamine-6,6'-disulfate disodium salt; N-Acetyl-6,6'-disulfo-lactosamine disodium salt; 6,6'-Disulfo-N-acetyllactosamine disodium salt; Disodium 6,6'-disulfo-N-acetyllactosamine; Galβ1-4GlcNAc-6,6'-disulfate disodium salt; N-Acetyllactosamine-6,6'-bis(sulfate) disodium salt; Lacto-N-biose I 6,6'-disulfate disodium salt
EINECS	Contact for details

Quality Control

Our n-Acetyllactosamine 6,6’-Disulfate Disodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure identity, potency, and consistency for research applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Endotoxin (LAL)	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.