Description

1-[(Ammoniooxy)Methyl]-4-(Trifluoromethyl)Benzene Chloride is a specialized organic salt featuring a reactive oxyamine (ammoniooxy) functional group. This compound is valued as a versatile building block in advanced organic synthesis, particularly for the introduction of functionalized benzyl motifs. It serves the needs of research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel molecular entities and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring trifluoromethylphenyl or oxyamine-linked pharmacophores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that benefit from the stability and lipophilicity of the trifluoromethyl group.
• Bioconjugation & Linker Chemistry: The reactive oxyamine group enables its use in bioconjugation strategies for labeling biomolecules or creating cleavable linkers in prodrug design.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and specialty materials with tailored surface properties.
• Chemical Biology Probes: Utilized in the synthesis of chemical probes for studying enzyme activity or protein function through targeted covalent modification.

Basic Information

Product Name	1-[(Ammoniooxy)Methyl]-4-(Trifluoromethyl)Benzene Chloride
CAS No.	321574-29-2
Molecular Formula	C9H9ClF3NO
Molecular Weight	239.62 g/mol
Synonyms	4-(Trifluoromethyl)benzyloxyammonium Chloride; O-(4-Trifluoromethylbenzyl)hydroxylammonium Chloride; (4-Trifluoromethylbenzyl)oxyammonium Chloride; 1-[(Ammoniooxy)Methyl]-4-(Trifluoromethyl)Benzene Chloride; α-(Aminooxy)-4-(trifluoromethyl)toluene Hydrochloride; 4-(Trifluoromethyl)benzyloxyamine HCl; Hydroxylamine, O-[(4-trifluoromethyl)phenyl]methyl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our production of 1-[(Ammoniooxy)Methyl]-4-(Trifluoromethyl)Benzene Chloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is characterized by advanced analytical techniques, including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. Due to its hygroscopic and oxidizable nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.