Description

1-(2,3,4-Trifluorophenyl)Ethan-1-Amine Hcl is a high-purity fluorinated aromatic amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity and electronic properties imparted by the trifluorophenyl group, enabling the development of novel compounds with enhanced stability and bioactivity. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms contribute to improved metabolic stability and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Utilized to create fluorinated analogs of biological molecules for mechanistic and diagnostic studies.

Basic Information

Product Name	1-(2,3,4-Trifluorophenyl)Ethan-1-Amine Hcl
CAS No.	321318-41-6
Molecular Formula	C8H8ClF3N
Molecular Weight	217.60 g/mol
Synonyms	1-(2,3,4-Trifluorophenyl)ethanamine hydrochloride; α-Methyl-2,3,4-trifluorobenzeneethanamine hydrochloride; 1-Aminoethyl-2,3,4-trifluorobenzene hydrochloride; 2,3,4-Trifluoro-α-methylbenzylamine hydrochloride; (1-(2,3,4-Trifluorophenyl)ethyl)amine hydrochloride; 2,3,4-Trifluoroamphetamine HCl; 1-(2,3,4-Trifluorophenyl)ethylamine HCl
EINECS	Contact for details

Quality Control

Our 1-(2,3,4-Trifluorophenyl)Ethan-1-Amine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Any individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.