Description

(R)-1-(3,5-Difluorophenyl)Ethanamine-Hcl is a high-purity chiral amine building block, essential for the synthesis of complex pharmaceutical intermediates and active ingredients. Its defined stereochemistry and fluorinated aromatic structure make it a critical component for developing targeted therapeutics with enhanced metabolic stability and receptor binding affinity. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for advanced R&D and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorinated phenyl group contributes to biological activity.
• Asymmetric Catalysis: Serves as a chiral ligand precursor or auxiliary in stereoselective synthesis to control the configuration of new chiral centers.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes and enzyme inhibitors to study biological pathways.
• Material Science Research: Investigated for the synthesis of specialty polymers and advanced organic materials with specific optical or electronic properties.

Basic Information

Product Name	(R)-1-(3,5-Difluorophenyl)Ethanamine Hydrochloride
CAS No.	321318-28-9
Molecular Formula	C8H10ClF2N
Molecular Weight	193.62 g/mol
Synonyms	(R)-1-(3,5-Difluorophenyl)ethanamine hydrochloride; (R)-α-Methyl-3,5-difluorobenzylamine hydrochloride; (R)-3,5-Difluoro-α-methylbenzylamine HCl; (R)-1-(3,5-Difluorophenyl)ethylamine hydrochloride; (R)-3,5-Difluorophenethylamine hydrochloride (common misnomer); (R)-1-(3,5-Difluoro-phenyl)-ethylamine HCl; (R)-Amphetamine, 3,5-difluoro-, hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(3,5-Difluorophenyl)Ethanamine-Hcl is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing assay, chiral purity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.