Description

4-Bromo-N'-Methyl-N'-[2-(Trifluoromethyl)-4-Quinazolinyl]Benzenesulfonohydrazide is a specialized, high-purity organic intermediate of significant interest in advanced chemical synthesis. Its core value lies in its unique molecular architecture, which incorporates a quinazoline core, a trifluoromethyl group, and a brominated benzenesulfonohydrazide moiety, making it a valuable building block for research and development. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel bioactive molecules, particularly in the areas of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Kinase Inhibitor Research: The quinazoline scaffold is a privileged structure in medicinal chemistry, making this compound a key starting material for developing potential kinase inhibitors.
• Agrochemical Development: Used in the research and synthesis of new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Chemical Biology Probes: Employed in the design and creation of molecular probes for studying biological processes and target validation.
• Organic Synthesis Building Block: Provides a versatile, multifunctional template for constructing complex molecules in academic and industrial research laboratories.
• Material Science Research: Potential use in the development of advanced organic materials due to its specific electronic properties imparted by the bromine and trifluoromethyl groups.

Basic Information

Product Name	4-Bromo-N'-Methyl-N'-[2-(Trifluoromethyl)-4-Quinazolinyl]Benzenesulfonohydrazide
CAS No.	320421-99-6
Molecular Formula	C₁₇H₁₃BrF₃N₄O₂S
Molecular Weight	473.28 g/mol
Synonyms	4-Bromo-N'-methyl-N'-[2-(trifluoromethyl)quinazolin-4-yl]benzenesulfonohydrazide; Benzenesulfonohydrazide, 4-bromo-N'-methyl-N'-[2-(trifluoromethyl)-4-quinazolinyl]-; 320421-99-6; 4-Bromo-N'-methyl-N'-(2-trifluoromethylquinazolin-4-yl)benzenesulfonohydrazide; 4-Bromo-N-methyl-N'-[2-(trifluoromethyl)-4-quinazolinyl]benzenesulfonohydrazide
EINECS	Contact for details

Quality Control

Our 4-Bromo-N'-Methyl-N'-[2-(Trifluoromethyl)-4-Quinazolinyl]Benzenesulfonohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound should be considered moisture-sensitive (hygroscopic); keep the container tightly sealed under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.