Description

5-(Trifluoromethyl)[1,2,4]Triazolo[4,3-C]Quinazoline is a high-value, heterocyclic organic compound featuring a fused triazoloquinazoline core substituted with a trifluoromethyl group. This advanced chemical intermediate is critical for research and development in medicinal chemistry, where its unique structure enables the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical entities with potential biological activity.
• Agrochemical Development: Serves as a precursor in the research of new herbicides and fungicides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science Research: Investigated as a potential component in the development of organic electronic materials due to its fused aromatic system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	5-(Trifluoromethyl)[1,2,4]Triazolo[4,3-C]Quinazoline
CAS No.	320421-82-7
Molecular Formula	C10H5F3N4
Molecular Weight	238.17 g/mol
Synonyms	5-(Trifluoromethyl)-[1,2,4]triazolo[4,3-c]quinazoline; 5-(Trifluoromethyl)-1,2,4-triazolo[4,3-c]quinazoline; [1,2,4]Triazolo[4,3-c]quinazoline, 5-(trifluoromethyl)-; 320421-82-7; 5-Trifluoromethyl[1,2,4]triazolo[4,3-c]quinazoline; 5-(Trifluoromethyl)-1H-[1,2,4]triazolo[4,3-c]quinazoline
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)[1,2,4]Triazolo[4,3-C]Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.