Description

3-Phenyl-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the central nervous system (CNS) and metabolic disease fields. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities (NCEs).
• Preclinical Development: Serves as a critical starting material for producing batches of active pharmaceutical ingredients (APIs) for toxicology and early-phase clinical studies.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying specific biological pathways and target validation.
• Contract Synthesis: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-complexity intermediates.

Basic Information

Product Name	3-Phenyl-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One Hydrochloride
CAS No.	320419-82-7
Molecular Formula	C16H21N3O2•HCl
Molecular Weight	323.82 g/mol (Free base: 287.36 g/mol)
Synonyms	3-Phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride; 1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 3-phenyl-, hydrochloride; 3-Phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one HCl; Spirocyclic oxadiazinone hydrochloride; 320419-82-7; 3-Phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one monohydrochloride
EINECS	Contact for details

Quality Control

Our 3-Phenyl-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or a nitrogen atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.