Description

7,8-Difluoroquinoline-3-Carboxylic Acid is a high-value fluorinated quinoline derivative serving as a critical building block in advanced organic synthesis. Its core value lies in the strategic placement of fluorine atoms, which can dramatically alter the physicochemical and biological properties of target molecules, making it indispensable for research and development. This compound is primarily needed by pharmaceutical, agrochemical, and advanced material scientists for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antibacterial, anticancer, and CNS-targeted drug discovery programs.
• Agrochemical Research: Used in the synthesis of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Precursor: Employed in the creation of organic semiconductors, liquid crystals, and fluorescent dyes due to the quinoline core's electronic properties.
• Chemical Biology Probe: Serves as a scaffold for developing molecular probes and diagnostic agents in biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the life sciences industry.

Basic Information

Product Name	7,8-Difluoroquinoline-3-Carboxylic Acid
CAS No.	318685-41-5
Molecular Formula	C10H5F2NO2
Molecular Weight	209.15 g/mol
Synonyms	3-Quinolinecarboxylic acid, 7,8-difluoro-; 7,8-Difluoro-3-quinolinecarboxylic acid; 7,8-Difluoroquinoline-3-carboxylic acid; Difluoroquinolinecarboxylic acid; CAS 318685-41-5; 318685-41-5
EINECS	Contact for details

Quality Control

Our 7,8-Difluoroquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.