Description

Ethyl 4-Chloro-6,7-Difluoroquinoline-3-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for constructing novel quinoline-based molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the biological activity of the difluoroquinoline scaffold.
• Material Science Research: Serves as a building block for creating organic semiconductors, ligands for catalysis, and fluorescent dyes due to its conjugated quinoline structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs) developing proprietary compounds.

Basic Information

Product Name	Ethyl 4-Chloro-6,7-Difluoroquinoline-3-Carboxylate
CAS No.	318685-01-7
Molecular Formula	C₁₂H₈ClF₂NO₂
Molecular Weight	271.65 g/mol
Synonyms	Ethyl 4-chloro-6,7-difluoro-3-quinolinecarboxylate; 4-Chloro-6,7-difluoroquinoline-3-carboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 4-chloro-6,7-difluoro-, ethyl ester; 318685-01-7; Ethyl 4-chloro-6,7-difluoroquinoline-3-carboxylate; 4-Chloro-6,7-difluorochinolin-3-carbonsäureethylester (German)
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-6,7-Difluoroquinoline-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.