Description

Glycine, n-(1-Thioxo-2-Propenyl)-, Methyl Ester (9Ci) is a specialized thiocarbonyl derivative of glycine, serving as a versatile building block in advanced organic synthesis. This compound is valued for its reactive thioamide and ester functional groups, which enable its use in the construction of complex heterocyclic and peptidomimetic structures. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of thiazole, thiazolidine, and other sulfur-containing heterocycles with potential biological activity.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that incorporate thiocarbonyl motifs.
• Peptidomimetics & Bio-conjugation: Serves as a constrained amino acid analog for creating modified peptides and for bio-conjugation strategies.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and enzyme inhibitors targeting cysteine proteases.
• Material Science: Acts as a monomer or cross-linking agent in the research of specialty polymers and functionalized surfaces.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Item	Detail
Product Name	Glycine, n-(1-Thioxo-2-Propenyl)-, Methyl Ester (9Ci)
CAS No.	318295-75-9
Molecular Formula	C6H9NO2S
Molecular Weight	159.21 g/mol
Synonyms	Methyl 2-[(1-thioxoprop-2-en-1-yl)amino]acetate; N-Acryloylglycine methyl ester thioamide; 2-[(1-Thioxoallyl)amino]acetic acid methyl ester; N-(1-Thioxo-2-propenyl)glycine methyl ester; Acrylglycine methyl ester thioamide; Allylthioamidoglycine methyl ester; (Methoxycarbonylmethyl)carbamothioic acid S-allyl ester (tautomer)
EINECS	Contact for details

Quality Control

Our Glycine, n-(1-Thioxo-2-Propenyl)-, Methyl Ester (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.