Description

(4-Trifluoromethyl-5,6,7,8-Tetrahydroquinazolin-2-Yl)Thiourea is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating a thiourea moiety and a trifluoromethyl group. This compound is of significant commercial interest due to its role as a key building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging the biological activity of the quinazoline core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Synthesis: Acts as a specialized building block for creating complex, high-value organic compounds for various industrial applications.

Basic Information

Product Name	(4-Trifluoromethyl-5,6,7,8-Tetrahydroquinazolin-2-Yl)Thiourea
CAS No.	318258-27-4
Molecular Formula	C10H9F3N4S
Molecular Weight	274.27 g/mol
Synonyms	1-(4-Trifluoromethyl-5,6,7,8-tetrahydroquinazolin-2-yl)thiourea; 2-Thioureido-4-trifluoromethyl-5,6,7,8-tetrahydroquinazoline; N-(4-Trifluoromethyl-5,6,7,8-tetrahydroquinazolin-2-yl)thiourea; 4-(Trifluoromethyl)-5,6,7,8-tetrahydro-2-quinazolinylthiourea; 318258-27-4; (4-Trifluoromethyl-5,6,7,8-tetrahydro-2-quinazolinyl)thiourea
EINECS	Contact for details

Quality Control

Our (4-Trifluoromethyl-5,6,7,8-Tetrahydroquinazolin-2-Yl)Thiourea is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.