Description

5-[1-(4-Fluorobenzyl)-1H-Pyrazol-3-Yl]-2-Phenyl-1,3-Thiazole is a high-value, heterocyclic organic compound featuring a unique molecular scaffold combining pyrazole and thiazole rings. This structure is of significant interest for its potential as a key intermediate in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector seeking to develop novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its privileged heterocyclic core.
• Agrochemical Development: Potential application as a precursor in the research and synthesis of new generation herbicides and fungicides.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with specific electronic or optical properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process scale-up services for the pharmaceutical and biotechnology industries.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-[1-(4-Fluorobenzyl)-1H-Pyrazol-3-Yl]-2-Phenyl-1,3-Thiazole
CAS No.	318255-97-9
Molecular Formula	C19H14FN3S
Molecular Weight	335.40 g/mol
Synonyms	2-Phenyl-5-[1-[(4-fluorophenyl)methyl]pyrazol-3-yl]-1,3-thiazole; 5-(1-(4-Fluorobenzyl)-1H-pyrazol-3-yl)-2-phenylthiazole; 318255-97-9; 5-[1-(4-Fluorobenzyl)-1H-pyrazol-3-yl]-2-phenylthiazole; 2-Phenyl-5-[1-(4-fluorobenzyl)-1H-pyrazol-3-yl]thiazole; 5-(1-(4-Fluorobenzyl)-1H-pyrazol-3-yl)-2-phenyl-1,3-thiazole
EINECS	Contact for details

Quality Control

Our 5-[1-(4-Fluorobenzyl)-1H-Pyrazol-3-Yl]-2-Phenyl-1,3-Thiazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.