Description

2-(Benzylsulfanyl)-3-Ethyl-5,6-Dihydrospiro(Benzo[H]Quinazoline-5,1'-Cyclopentane)-4(3H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic quinazoline structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily sought after by R&D laboratories and pharmaceutical manufacturers engaged in creating new therapeutic agents, especially those targeting central nervous system disorders or oncological pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly those with spirocyclic architectures.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and validation in QC laboratories.
• Biochemical Research: Potential use in probing enzyme interactions or as a ligand in biochemical assays due to its heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	2-(Benzylsulfanyl)-3-Ethyl-5,6-Dihydrospiro(Benzo[H]Quinazoline-5,1'-Cyclopentane)-4(3H)-One
CAS No.	316362-61-5
Molecular Formula	C24H26N2OS
Molecular Weight	390.54 g/mol
Synonyms	3-Ethyl-2-(phenylmethylthio)-5,6-dihydrospiro[benzo[h]quinazoline-5,1'-cyclopentane]-4(3H)-one; 2-(Benzylthio)-3-ethyl-5,6-dihydrospiro[benzo[h]quinazoline-5,1'-cyclopentane]-4(3H)-one; Spiro[benzo[h]quinazoline-5,1'-cyclopentane]-4(3H)-one, 2-(benzylthio)-3-ethyl-5,6-dihydro-; CAS 316362-61-5
EINECS	Contact for details

Quality Control

Our 2-(Benzylsulfanyl)-3-Ethyl-5,6-Dihydrospiro(Benzo[H]Quinazoline-5,1'-Cyclopentane)-4(3H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.