Description

2-Chloro-n-(4-(n-(2,6-Dimethoxypyrimidin-4-Yl)Sulfamoyl)Phenyl)Benzamide is a high-purity, advanced pharmaceutical intermediate with a complex sulfonamide-benzamide hybrid structure. This compound is of significant value for its role in the research and development of novel therapeutic agents, particularly in targeted drug discovery programs. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing new chemical entities (NCEs) for potential use in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a critical precursor in the multi-step synthesis of complex target molecules for preclinical and clinical trials.
• Biochemical Research: Employed as a tool compound or reference standard in biochemical assays to study protein-ligand interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional laboratories for advanced organic synthesis and pharmacological research.

Basic Information

Product Name	2-Chloro-n-(4-(n-(2,6-Dimethoxypyrimidin-4-Yl)Sulfamoyl)Phenyl)Benzamide
CAS No.	314766-26-2
Molecular Formula	C19H16ClN5O5S
Molecular Weight	469.88 g/mol
Synonyms	2-Chloro-N-[4-[[(2,6-dimethoxypyrimidin-4-yl)amino]sulfonyl]phenyl]benzamide; Benzamide, 2-chloro-N-[4-[[(2,6-dimethoxy-4-pyrimidinyl)amino]sulfonyl]phenyl]-; 2-Chloro-N-(4-((2,6-dimethoxypyrimidin-4-yl)sulfamoyl)phenyl)benzamide; 2-Chloro-N-(4-(N-(2,6-dimethoxypyrimidin-4-yl)sulfamoyl)phenyl)benzamide; 314766-26-2; Sulfonamide-benzamide hybrid intermediate
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-n-(4-(n-(2,6-Dimethoxypyrimidin-4-Yl)Sulfamoyl)Phenyl)Benzamide adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.