Description

Carbamic Acid, [(2S)-2-Amino-3-Methoxypropyl]-, 1,1-Dimethylethyl Ester (9Ci) is a chiral, protected amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a crucial building block for the development of novel pharmaceuticals and bioactive molecules, offering a versatile handle for peptide coupling and molecular diversification. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for neurological and metabolic drugs.
• Peptide Chemistry: Used as a protected amino acid derivative for the solid-phase and solution-phase synthesis of modified peptides and peptidomimetics.
• Protease Inhibitor Research: Serves as a core structural component in the development of novel enzyme inhibitors targeting specific proteases.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein function.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective catalytic reactions to construct complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global pharmaceutical pipeline.

Basic Information

Product Name	Carbamic Acid, [(2S)-2-Amino-3-Methoxypropyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	314757-44-3
Molecular Formula	C9H20N2O3
Molecular Weight	204.27 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-O-methyl-L-serinol; (2S)-2-[(tert-Butoxycarbonyl)amino]-3-methoxy-1-propanol; tert-Butyl N-[(2S)-2-amino-3-methoxypropyl]carbamate; Boc-L-Serinol methyl ether; Boc-Ser(OMe)-ol; (S)-2-((tert-Butoxycarbonyl)amino)-3-methoxypropan-1-ol; N-Boc-O-methyl-L-serinol; L-Serinol, N-Boc, O-methyl
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(2S)-2-Amino-3-Methoxypropyl]-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with stringent industry standards for research and pharmaceutical use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.