Description

1-(3-(6-Bromo-2-Methyl-4-Phenylquinolin-3-Yl)-5-(4-Fluorophenyl)-4,5-Dihydro-1H-Pyrazol-1-Yl)Ethan-1-One is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the research and development of novel therapeutic agents, particularly in oncology and targeted drug discovery. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Kinase Inhibitor Development: Serves as a core scaffold for the development of potential kinase inhibitors due to its quinoline and pyrazole motifs.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological processes and target identification.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CRMOs) for client-specific synthetic routes.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	1-(3-(6-Bromo-2-Methyl-4-Phenylquinolin-3-Yl)-5-(4-Fluorophenyl)-4,5-Dihydro-1H-Pyrazol-1-Yl)Ethan-1-One
CAS No.	313967-94-1
Molecular Formula	C27H21BrFN3O
Molecular Weight	502.38 g/mol
Synonyms	1-[3-(6-Bromo-2-methyl-4-phenyl-3-quinolyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone; 1-[3-(6-Bromo-2-methyl-4-phenylquinolin-3-yl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one; Ethanone, 1-[3-(6-bromo-2-methyl-4-phenyl-3-quinolinyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]-; 313967-94-1; 6-Bromo-2-methyl-4-phenyl-3-[5-(4-fluorophenyl)-1-acetyl-4,5-dihydro-1H-pyrazol-3-yl]quinoline
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development and commercial projects requiring material suitable for use under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.