Description

Spiro[1-Azabicyclo[2.2.2]Octane-3,4'-Imidazolidin]-2'-One Hydrochloride is a high-purity, complex heterocyclic organic compound with the CAS number 313643-41-3. This advanced pharmaceutical intermediate is valued for its unique spirocyclic structure, which is critical for imparting specific biological activity in drug discovery and development. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly within the fields of central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize lead compounds for potency and selectivity.
• Preclinical Development: Serves as a critical material for producing batches of candidate drugs for pharmacological and toxicological evaluation.
• Academic Research: Employed in universities and research institutes studying nitrogen-containing heterocycles and their biological interactions.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for scale-up synthesis under cGMP conditions.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control.

Basic Information

Product Name	Spiro[1-Azabicyclo[2.2.2]Octane-3,4'-Imidazolidin]-2'-One Hydrochloride
CAS No.	313643-41-3
Molecular Formula	C10H16ClN3O
Molecular Weight	229.71 g/mol
Synonyms	Spiro[1-azabicyclo[2.2.2]octane-3,4'-imidazolidin]-2'-one hydrochloride; 1-Azabicyclo[2.2.2]octane-3-spiro-4'-imidazolidin-2'-one hydrochloride; 3-Spiroimidazolidin-2-one-1-azabicyclo[2.2.2]octane hydrochloride; Quinuclidine-3-spiro-4'-imidazolidin-2'-one hydrochloride; 313643-41-3; Spiro(quinuclidine-3,4'-imidazolidin)-2'-one hydrochloride
EINECS	Contact for details

Quality Control

Our Spiro[1-Azabicyclo[2.2.2]Octane-3,4'-Imidazolidin]-2'-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.