Description

4-((6-Methyl-4-Phenylquinazolin-2-Yl)Amino)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct quinazoline-benzoic acid hybrid structure. This compound matters for its critical role as a key building block in the synthesis of targeted therapeutic agents, particularly in oncology and kinase inhibitor research. Pharmaceutical R&D laboratories and fine chemical manufacturers need it to develop novel drug candidates with enhanced biological activity and specificity. Its precise molecular architecture offers a versatile scaffold for further chemical modifications.

Application

• Primary building block for the synthesis of novel kinase inhibitor candidates in pharmaceutical research.
• Key intermediate in the development of targeted anticancer agents and chemotherapeutics.
• Precursor for advanced pharmaceutical intermediates with quinazoline-based pharmacophores.
• Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Research chemical in biochemical assays and high-throughput screening (HTS) for drug discovery.
• Starting material for custom synthesis services in contract research organizations (CROs) and contract development and manufacturing organizations (CDMOs).

Basic Information

Product Name	4-((6-Methyl-4-Phenylquinazolin-2-Yl)Amino)Benzoic Acid
CAS No.	313398-29-7
Molecular Formula	C22H17N3O2
Molecular Weight	355.39 g/mol
Synonyms	4-[(6-Methyl-4-phenylquinazolin-2-yl)amino]benzoic acid; 2-[(4-Carboxyphenyl)amino]-6-methyl-4-phenylquinazoline; Benzoic acid, 4-((6-methyl-4-phenyl-2-quinazolinyl)amino)-; 4-(6-Methyl-4-phenylquinazolin-2-ylamino)benzoic acid; 313398-29-7; 4-((6-Methyl-4-phenylquinazolin-2-yl)amino)benzoic acid; 4-[(6-Methyl-4-phenyl-2-quinazolinyl)amino]benzoic acid
EINECS	Contact for details

Quality Control

Our 4-((6-Methyl-4-Phenylquinazolin-2-Yl)Amino)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure compliance with research and pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided to guarantee batch-to-batch consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.