Description

4-[(6-Chloro-4-Phenylquinazolin-2-Yl)Amino]Benzoic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS number 313398-28-6. This compound is a critical building block in the synthesis of targeted therapeutic agents, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily utilized by the pharmaceutical and biotechnology industries for research and development (R&D) and commercial production of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex quinazoline-based active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Development: Serves as a core scaffold for research into novel tyrosine kinase inhibitors for oncology applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Research: Employed as a tool compound in biochemical assays and target validation studies.
• Custom Synthesis: A starting point for the contract manufacturing of specialized, non-commercial drug substances.

Basic Information

Product Name	4-[(6-Chloro-4-Phenylquinazolin-2-Yl)Amino]Benzoic Acid
CAS No.	313398-28-6
Molecular Formula	C21H14ClN3O2
Molecular Weight	375.81 g/mol
Synonyms	4-[(6-Chloro-4-phenylquinazolin-2-yl)amino]benzoic acid; 4-((6-Chloro-4-phenylquinazolin-2-yl)amino)benzoic acid; Benzoic acid, 4-[(6-chloro-4-phenyl-2-quinazolinyl)amino]-; 313398-28-6; 4-(6-Chloro-4-phenylquinazolin-2-ylamino)benzoic acid; 2-Quinazolinamine, N-(4-carboxyphenyl)-6-chloro-4-phenyl-; N-(4-Carboxyphenyl)-6-chloro-4-phenyl-2-quinazolinamine
EINECS	Contact for details

Quality Control

Our 4-[(6-Chloro-4-Phenylquinazolin-2-Yl)Amino]Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.