Description

n-[(1S,2S)-2-Aminocyclohexyl]-1,1,1-Trifluoro-Methanesulfonamide is a high-purity, chiral trifluoromethanesulfonamide derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and ligand precursor for the development of novel pharmaceuticals and agrochemicals. It is primarily utilized by research institutions and industrial R&D departments focused on asymmetric catalysis, medicinal chemistry, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective synthesis to produce single-isomer compounds.
• Agrochemical Research: Employed in the discovery and synthesis of novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Used in the development of specialty polymers and advanced materials where the introduction of a chiral, fluorinated moiety can modify physical properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in contract research organizations (CROs).

Basic Information

Product Name	n-[(1S,2S)-2-Aminocyclohexyl]-1,1,1-Trifluoro-Methanesulfonamide
CAS No.	313342-12-0
Molecular Formula	C7H13F3N2O2S
Molecular Weight	246.25 g/mol
Synonyms	(1S,2S)-N-(2-Aminocyclohexyl)-1,1,1-trifluoromethanesulfonamide; (1S,2S)-2-Amino-N-(trifluoromethylsulfonyl)cyclohexanamine; 1,1,1-Trifluoro-N-[(1S,2S)-2-aminocyclohexyl]methanesulfonamide; (1S,2S)-2-Aminocyclohexyl Trifluoromethanesulfonamide; (1S,2S)-TfNH-Cyclohexane-1,2-diamine derivative; Chiral Cyclohexyl Triflamide; (1S,2S)-2-ATFMSA
EINECS	Contact for details

Quality Control

Our n-[(1S,2S)-2-Aminocyclohexyl]-1,1,1-Trifluoro-Methanesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.