Description

6-Bromo-2-(3-Hydroxyphenyl)Quinoline-4-Carboxylic Acid is a high-purity, functionalized quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic combination of a bromo substituent and a carboxylic acid group on the quinoline core, which enables precise downstream functionalization for creating complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for organic light-emitting diodes (OLEDs) and other functional organic electronic materials.
• Ligand and Catalyst Development: The carboxylic acid and hydroxyl groups make it a useful scaffold for creating chelating ligands in coordination chemistry and catalysis.
• Fluorescent Probe Synthesis: Utilized in the design of quinoline-based fluorescent markers and sensors for biological imaging.
• Academic & Contract Research: A valuable reagent for methodology development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	6-Bromo-2-(3-Hydroxyphenyl)Quinoline-4-Carboxylic Acid
CAS No.	313241-30-4
Molecular Formula	C₁₆H₁₀BrNO₃
Molecular Weight	344.16 g/mol
Synonyms	6-Bromo-2-(3-hydroxyphenyl)-4-quinolinecarboxylic acid; 2-(3-Hydroxyphenyl)-6-bromoquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 6-bromo-2-(3-hydroxyphenyl)-; 313241-30-4; 6-Bromo-2-(3-hydroxyphenyl)chinolin-4-carbonsäure (German); Acide 6-bromo-2-(3-hydroxyphenyl)quinoléine-4-carboxylique (French)
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(3-Hydroxyphenyl)Quinoline-4-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced intermediate production where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.