Description

Ethyl [(3-Cyclopentyl-4-Oxo-3,4,5,6-Tetrahydrospiro{Benzo[H]Quinazoline-5,1'-Cyclopentane}-2-Yl)Sulfanyl]Acetate is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and quinazoline-based molecular architecture. This compound is of significant value for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily targeted at pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially those focused on central nervous system (CNS) or oncology targets.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates, particularly those with quinazoline or spirocyclic scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop compounds with targeted biological activity.
• API Synthesis: Employed in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), especially for complex small-molecule drugs.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a probe to study specific enzyme interactions or biological pathways in academic and industrial research settings.
• Fine Chemical Production: Acts as a specialized intermediate for contract manufacturing organizations (CMOs) and CDMOs producing custom compounds for clinical trials.

Basic Information

Item	Details
Product Name	Ethyl [(3-Cyclopentyl-4-Oxo-3,4,5,6-Tetrahydrospiro{Benzo[H]Quinazoline-5,1'-Cyclopentane}-2-Yl)Sulfanyl]Acetate
CAS No.	312625-92-6
Molecular Formula	C26H32N2O3S
Molecular Weight	452.61 g/mol
Synonyms	Ethyl 2-[(3-cyclopentyl-4-oxo-5,6-dihydrospiro[benzo[h]quinazoline-5,1'-cyclopentane]-2-yl)thio]acetate; Spiro[benzo[h]quinazoline-5,1'-cyclopentane] derivative; 2-[(3-Cyclopentyl-4-oxo-3,4,5,6-tetrahydrospiro[benzo[h]quinazoline-5,1'-cyclopentane]-2-yl)thio]acetic acid ethyl ester; UNII-9V6T7Q6H8I; 9V6T7Q6H8I; Ethyl (3-cyclopentyl-4-oxo-3,4,5,6-tetrahydrospiro[benzo[h]quinazoline-5,1'-cyclopentane]-2-yl)sulfanylacetate
EINECS	Contact for details

Quality Control

Our Ethyl [(3-Cyclopentyl-4-Oxo-3,4,5,6-Tetrahydrospiro{Benzo[H]Quinazoline-5,1'-Cyclopentane}-2-Yl)Sulfanyl]Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.