Description

1-(Phenylsulfonyl)Piperidine-4-Carbohydrazide is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. This compound matters as a versatile intermediate, offering a unique molecular scaffold that combines a sulfonamide-protected piperidine ring with a reactive hydrazide functional group. It is primarily needed by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring complex heterocyclic architectures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the piperidine-hydrazide moiety can contribute to biological activity.
• Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex sulfonamides, hydrazones, and fused heterocyclic compounds in academic and industrial R&D.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for metal catalysis or as a scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, advanced intermediates.

Basic Information

Product Name	1-(Phenylsulfonyl)Piperidine-4-Carbohydrazide
CAS No.	312534-14-8
Molecular Formula	C12H17N3O3S
Molecular Weight	283.35 g/mol
Synonyms	4-Hydrazinylcarbonyl-1-(phenylsulfonyl)piperidine; 1-(Benzenesulfonyl)-4-(hydrazinecarbonyl)piperidine; 1-(Phenylsulfonyl)-4-piperidinecarbohydrazide; Piperidine-4-carbohydrazide, 1-(phenylsulfonyl)-; 4-Carbohydrazido-1-(phenylsulfonyl)piperidine; 1-Phenylsulfonylpiperidine-4-carbohydrazide; N'-(1-Phenylsulfonylpiperidin-4-yl)hydrazinecarboxamide
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)Piperidine-4-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and loss on drying for moisture content, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.