Description

p-Methoxybenzyl Trityl Ether 97 is a specialized protecting group reagent widely used in synthetic organic chemistry. Its primary value lies in its orthogonal protecting group strategy, allowing for the selective protection and deprotection of hydroxyl groups in complex multi-step syntheses. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of complex molecules like nucleosides, carbohydrates, and natural products where precise control over functional group manipulation is critical.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the protection of hydroxyl groups during the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Nucleoside & Nucleotide Chemistry: Used in the preparation of protected nucleoside building blocks for oligonucleotide and prodrug development.
• Carbohydrate & Glycochemistry: Employed for the selective protection of sugar hydroxyls in the synthesis of complex oligosaccharides and glycoconjugates.
• Peptide & Natural Product Synthesis: Facilitates the construction of complex molecular architectures by providing a stable, acid-labile protecting group that is orthogonal to other common protecting groups.
• Process Chemistry & Scale-up: Suitable for development from laboratory-scale research to pilot and commercial-scale manufacturing of fine chemicals.
• Academic & Industrial R&D: A staple reagent in research laboratories for methodological development and the exploration of new synthetic pathways.

Basic Information

Product Name	p-Methoxybenzyl Trityl Ether 97
CAS No.	312493-51-9
Molecular Formula	C27H24O2
Molecular Weight	380.48 g/mol
Synonyms	PMB-Tr Ether; 4-Methoxybenzyl Trityl Ether; 1-[(4-Methoxyphenyl)methoxy]-1,1-diphenylmethane; (4-Methoxybenzyloxy)triphenylmethane; p-Methoxybenzyloxy-triphenylmethane; Trityl PMB Ether; PMBTrt-OH; MPM-Trityl Ether
EINECS	Contact for details

Quality Control

Our p-Methoxybenzyl Trityl Ether 97 is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed to confirm identity and purity, with comprehensive testing including chromatographic purity and residual solvent analysis. Certificates of Analysis (COA) are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The product is stable under these conditions but should be handled in accordance with good laboratory practices for moisture-sensitive and light-sensitive materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.