Description

2-Amino-4-(5-Bromo-2-Thienyl)-7,7-Dimethyl-5-Oxo-1-[3-(Trifluoromethyl)Phenyl]-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in medicinal chemistry programs targeting specific enzyme inhibition. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique quinoline and thiophene motifs.
• Chemical Biology Probes: Serves as a precursor for developing specialized molecular probes to study biological pathways and protein interactions.
• Academic & Institutional Research: Employed in university and institutional labs for advanced organic synthesis and heterocyclic chemistry projects.
• Custom Synthesis: Starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client-specific drug discovery programs.
• Library Synthesis: Valuable scaffold for generating diverse compound libraries for high-throughput screening (HTS) in early-stage drug discovery.

Basic Information

Product Name	2-Amino-4-(5-Bromo-2-Thienyl)-7,7-Dimethyl-5-Oxo-1-[3-(Trifluoromethyl)Phenyl]-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile
CAS No.	311765-27-2
Molecular Formula	C23H19BrF3N3OS
Molecular Weight	522.38 g/mol
Synonyms	1,4,5,6,7,8-Hexahydro-2-amino-4-(5-bromo-2-thienyl)-7,7-dimethyl-5-oxo-1-[3-(trifluoromethyl)phenyl]-3-quinolinecarbonitrile; 3-Quinolinecarbonitrile, 2-amino-4-(5-bromo-2-thienyl)-1,4,5,6,7,8-hexahydro-7,7-dimethyl-5-oxo-1-[3-(trifluoromethyl)phenyl]-; 2-Amino-4-(5-bromo-2-thienyl)-7,7-dimethyl-5-oxo-1-(3-trifluoromethylphenyl)-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile; CAS 311765-27-2
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(5-Bromo-2-Thienyl)-7,7-Dimethyl-5-Oxo-1-[3-(Trifluoromethyl)Phenyl]-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is kept tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.