Description

2-Amino-4-(4-Ethylphenyl)-1-{3-Nitrophenyl}-5-Oxo-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex polycyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for complex heterocyclic targets.

Application

This specialized quinoline derivative serves as a versatile intermediate in advanced chemical synthesis. Key application areas include:

• Pharmaceutical Intermediate: Core building block for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Organic Synthesis Research: A key starting material for academic and industrial research into novel polycyclic heterocyclic compounds and their structure-activity relationships (SAR).
• Process Chemistry Development: Used in scaling up and optimizing synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) guidelines.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Agrochemical Research: Potential intermediate in the discovery of new agrochemicals with specific biological activity.

Basic Information

Product Name	2-Amino-4-(4-Ethylphenyl)-1-{3-Nitrophenyl}-5-Oxo-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile
CAS No.	311328-90-2
Molecular Formula	C24H22N4O3
Molecular Weight	414.46 g/mol
Synonyms	2-Amino-4-(4-ethylphenyl)-1-(3-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarbonitrile; 1,4,5,6,7,8-Hexahydro-2-amino-4-(4-ethylphenyl)-1-(3-nitrophenyl)-5-oxo-3-quinolinecarbonitrile; 3-Quinolinecarbonitrile, 2-amino-4-(4-ethylphenyl)-1-(3-nitrophenyl)-1,4,5,6,7,8-hexahydro-5-oxo-; CAS 311328-90-2; 2-Amino-4-(p-ethylphenyl)-1-(m-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile; Advanced Quinoline Intermediate 311328-90-2
EINECS	Contact for details

Quality Control

Our production of 2-Amino-4-(4-Ethylphenyl)-1-{3-Nitrophenyl}-5-Oxo-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality system is designed to support applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.