Description

2-Amino-1-(3-Chloro-2-Methylphenyl)-7,7-Dimethyl-5-Oxo-4-(3-Pyridinyl)-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex polycyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need this precise chemical entity to develop next-generation drug candidates targeting complex diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based active pharmaceutical ingredients (APIs).
• Drug Discovery & Development: Used in medicinal chemistry research for constructing complex heterocyclic cores in screening libraries.
• Chemical Biology Research: Serves as a scaffold for developing enzyme inhibitors or receptor modulators in biochemical studies.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating structurally complex molecules.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for advanced organic methodology and heterocyclic chemistry studies.

Basic Information

Item	Details
Product Name	2-Amino-1-(3-Chloro-2-Methylphenyl)-7,7-Dimethyl-5-Oxo-4-(3-Pyridinyl)-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile
CAS No.	311324-62-6
Molecular Formula	C24H23ClN4O
Molecular Weight	418.92 g/mol
Synonyms	2-Amino-1-(3-chloro-2-methylphenyl)-7,7-dimethyl-5-oxo-4-(pyridin-3-yl)-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile; 3-Quinolinecarbonitrile, 2-amino-1-(3-chloro-2-methylphenyl)-7,7-dimethyl-5-oxo-4-(3-pyridinyl)-1,4,5,6,7,8-hexahydro-; CAS 311324-62-6; Hexahydroquinolinecarbonitrile derivative; Amino-chloro-methylphenyl-dimethyl-oxo-pyridinyl-hexahydroquinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-1-(3-Chloro-2-Methylphenyl)-7,7-Dimethyl-5-Oxo-4-(3-Pyridinyl)-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request, supporting compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.